Guide

Drug clinical-trial sponsor: prepare and file the regulatory application with Health Canada

Classify the trial, assemble protocol, quality and clinical records, obtain ethics and sites, then manage amendments and incidents.

Priority

No person should be recruited or exposed to the product before applicable regulatory and ethics authorizations and site activation.

Confirm the scope

Define the sponsor, product, indication, phase, population, protocol, comparator, importation, manufacture and Canadian sites.

Prepare the information

Assemble forms, brochure, protocol, consent, clinical and non-clinical data and chemistry-manufacturing records in the required format.

Complete the process

File the application, answer clarification requests and obtain research-ethics approval and information for every site.

Keep follow-up records

After authorization, control product, consent, monitoring, incidents, amendments, suspension, closure and record retention.

Clinical Trial Applications — Health Canada

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Official sources are linked in the guide. Checked August 29, 2026; confirm current rules, forms and deadlines with the responsible authority.
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